This study evaluated the effect of silver nanoparticles (Ag NPs) on nodal segments surface disinfection, plant growth regulators on axillary shoot multiplication, and indole-3-butyric acid (IBA) on rooting of in vitro-regenerated shoots in Monstera deliciosa Liebm. ‘Thai Constellation’. The surface disinfection of the nodal explants was achieved best with immersion in 70% (v : v) ethanol for 90 s, followed by sodium hypochlorite (1.0%, v : v) for 10 min, and finally 80 mg l^-1 Ag NPs for 50 min. The surface disinfected nodal segments (0.8-1.0 cm) were cultivated on Murashige and Skoog (MS) medium with various concentrations of cytokinins (N⁶-benzyladenine, kinetin, and thidiazuron) and a combination of thidiazuron and α-naphthaleneacetic acid (NAA) for axillary shoot multiplication. The maximum shoot induction (100%) and a greater number of shoots (7.6) were achieved on MS medium with 4 µM thidiazuron and 2 µM NAA. Axillary shoots (> 2.0 cm) regenerated from nodal explants of M. deliciosa ‘Thai Constellation’ were separated and subcultured on MS medium supplemented with 0.5 g l^-1 activated charcoal and 0, 2, 4, 8, or 16 µM of IBA to induce rooting. The best rooting rate (100%) and highest number of roots (6.3) were obtained on MS medium with 0.5 g l^-1 activated charcoal and 8 µM IBA.