An innovative method for mass shoot propagation of Paphiopedilum delenatii ('Pink' slipper orchid), an endemic and endangered species of Vietnam, was established in this study. Nine-month-old seeds cultured on Knudson C medium was the optimal condition for in vitro germination. Seeds began swelling and became greenish in color after 30 to 40 days of culture. Then, rounded bodies, known as protocorms, were observed. Leaves and roots developed after 90-100 days of subculturing on the same medium. The combination of wounding and liquid culture was shown to be appropriate for highly frequent adventitious shoot formation. Shoot regeneration rate of 5.2 per wounded seedling could be obtained in MS liquid media supplemented with 1.0 mg l^-1 TDZ via this method.